ZFIN Image: Wolman et al., 2015, Fig. 6

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Figure Caption

Fig. 6

PAPP-AA Mediates Habituation through Acute Regulation of IGF Signaling

(A) Mean acoustic startle habituation percentage at 5 dpf of larvae treated with DMSO or 1 µM SC79. Treatment period (dpf) indicated below bars.

(B) Mean acoustic startle habituation percentage of 5 dpf larvae treated with 740 Y-P for 30 min prior to and during habituation assay.

(C and D) Mean acoustic startle habituation percentage after 30 min treatment with BMS-754807 or DMSO at 5 dpf (C) or 12 dpf (D). p < 0.01, p < 0.001, ANOVA with Bonferonni correction versus DMSO-treated larvae of the same genotype. N = number of larvae shown within bars. Error bars indicate SEM.

Figure Data

Phenotype details

Acknowledgments

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