IMAGE

Fig. 4

ID

ZDB-IMAGE-160310-5

Genes

EGFP
mCherry

Source

Figures for Chen et al., 2016

Image

Figure Caption

Fig. 4

gadd45ba and gadd45bb overexpression in podocytes aggravates MTZ-induced proteinuria. (a) Representative fluorescence figures showing disruption of the glomerular filtration barrier by MTZ leads to accumulation of GFP fluorescence in the proximal tubules (arrowheads) in Tg(pod:Gal4;UAS-NTR-mCherry; lfabp:VDBP-GFP). mCherry fluorescence (arrows) is reduced in glomeruli and accumulated in proximal tubules presumably due to podocytes loss. (b) Quantitation of GFP by ELISA showing zebrafish expressing gadd45ba/b in podocytes exhibit more poteinuria induced following MTZ-induced podocyte injury. Results are represented as mean±S.D. (n=3), *P<0.01 versus NTR group; Δ P<0.01 versus NTR and gadd45bb group

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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