ZFIN Image: Auer et al., 2015, Fig. 5, S3

Image

Figure Caption

Fig. 5, S3 Retinal Ganglion Cells show a normal mitochondria distribution in blumenkohl mutants.

(A) Distribution of mitochondria (labeled by mitoGFP) in single blumenkohl mutant and wild-type RGC arbors expressing membrane localized RFP (RFPCaax) in vivo. Upper two panels: blumenkohl mutant cell arbors at 5 and 7 dpf, lower two panels: wild-type cell arbors at 5 and 7 dpf. D = dorsal, V = ventral, R = rostral, C = caudal. Scale bars = 20 µm. (B) Transmission electron micrograph of a transvers section of the blumenkohl mutant neuropil containing RGC axonal arbors. In yellow circles: mitochondria. Scale bar = 500 nm. (C) Quantification of mitochondria area per neuropil area comparing wildtype, blumenkohl and kif5aa mutant tecta at 6 dpf. No difference is observed between wild-type and blumenkohl mutant cells while kif5aa mutants contain significantly less mitochondria than wild-type cells (p < 0.01). The graphs for kif5aa and wild-type cells were taken from Figure 5.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife