ZFIN Image: Cardozo et al., 2014, Fig. 3

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Figure Caption

Fig. 3

(a–d) Lateral views of control or cdon^ATG morphants treated with DMSO (vehicle) or cyclopamine from 90% epiboly and analysed with ISH for pax2.1 expression at 28 hpf. Blocking Hh signalling abolished pax2.1 expression in the optic stalk in wt embryos (c). In cdon^ATG morphants, cyclopamine treatment counteracts the expansion of pax2.1 overexpression observed in cdon^ATGMO injected embryos (a,b,d). The lens and the body are outlined with black and white dashed lines in (a–d). Arrows indicate the extent of the pax2.1 expression in the optic stalk. DMSO, dimethyl sulphoxide; MHB, midbrain–hindbrain boundary; oc, optic cup; os, optic stalk. Scale bar, 100 μm.

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Expression / Labeling details

Acknowledgments

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