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Fig. S9
The effects of MGCD0103 treatment are not reversible.
(A) Schematic representation of fin regeneration progression and MGCD0103 treatment. Fish were treated with DMSO or MGCD0103 for 10 days starting from the time of amputation and then fish were transferred into normal fish water for 10 additional days. (B) Corresponding images of whole caudal fins just after amputation (0 hpa), at 10 dpa or at 20 dpa. Effects of MGCD0103 treatment were not reversible. In some cases, a few rays were able to resume the regeneration process. Arrowheads indicate the amputation plane.
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