Image
|
Figure Caption
Fig. S14
Hdac1 inhibition after blastema formation is sufficient to block reactivation of osteocalcin expression.
(A) Caudal fins of osteocalcin:GFP transgenic fish at 3 dpa and 7 dpa treated with DMSO or MGCD0103 starting at 3 dpa. osteocalcin:GFP expression was not reactivated in fin regenerates treated with MGCD0103 after blastema has been formed. (B) Uninjured caudal fins of osteocalcin:GFP transgenic fish before and 10 days after MGCD0103 treatment. MGCD0103 treatment does not alter osteocalcin:GFP expression in uninjured fins. Constant exposure times were used. Scale bars: 100 μm.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ BMC Biol.