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Fig. S1
VegfA MO knockdown does not affect endocardial differentiation while arterial differentiation is perturbed.
(A-F) Endocardial (arrows) NFATc1 (A,B), cdh5 (C,D) and fli1 expression (E,F) is not significantly affected in VegfA MO injected embryos. Dorsal view of flat-mounted embryos, anterior is to the top. (G,H) Arterial grl expression (arrowheads, G) is absent in Vegf morphants, which confirms the efficacy of Vegf MO. Lateral view of the trunk region, anterior it to the left. The remaining grl expression in Vegf morphants is non-vascular.
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Reprinted from Developmental Biology, 361(2), Wong, K.S., Rehn, K., Palencia-Desai, S., Kohli, V., Hunter, W., Uhl, J.D., Rost, M.S., and Sumanas, S., Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish, 377-91, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.