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Fig. 8
Combined loss of ppp1r14al and fgf8 function leads to disruption of the r4 signaling center. Uninjected (A, E, I), fgf8 MO-injected (B, F, J), ppp1r14al MO-injected (C, G, K) or fgf8 + ppp1r14al MO-injected embryos (D, H, L) were assayed for expression of krox20 (A–D), pea3 (E–H) or valentino (I–L) by in situ hybridization. All embryos are dorsal views at 11hpf with anterior to the left.
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Reprinted from Developmental Biology, 358(2), Choe, S.K., Zhang, X., Hirsch, N., Straubhaar, J., and Sagerström, C.G., A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center, 356-67, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.