ZFIN Image: Palencia-Desai et al., 2011, Fig. S5

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Figure Caption

Fig. S5 A mixture of two different foxc1a MOs effectively inhibits endocardial differentiation but does not cause myocardial expansion. (A-H) hand2 (A,B) and cmlc2 (C,D) expression is not affected in Foxc1a morphant embryos, as analyzed by in situ hybridization at the 10-somite (A-D) and 20-somite (E-H) stages. (E,F) nfatc1 expression is absent in foxc1a MO cocktail-injected embryos. (G,H) kdrl:GFP endocardial expression is severely reduced in foxc1a MO cocktail-injected embryos. Endocardium was pseudocolored in green for illustration purpose. (A-H) Flat-mounted ventral views, anterior is upwards. (I) Percentages of foxc1a MO cocktail-injected embryos exhibiting defects in endocardial and myocardial marker expression. No embryos showed expansion in hand2 or cmlc2 expression.

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Acknowledgments

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