ZFIN Image: Eames et al., 2011, Fig. 10

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Figure Caption

Fig. 10

Early molecular markers of chondrocyte maturation in fam20b and xylt1 mutants.

A–R, horizontal section in situ hybridization of developing ceratohyals. The levels of runx2b transcripts appeared higher in chondrocytes (c) and perichondrium (pc) of the ceratohyal in fam20b^b1127 (B) and xylt1^b1128 (C) mutants, than in wild types (A) at 72 hpf. Expression of col10a1 was abundant in chondrocytes (c) and perichondrium (pc) of the ceratohyal in fam20b^b1127 (E) and xylt1^b1128 (F) mutants, but was not detectable in wild types (D) at 83 hpf. Levels of ihha and ihhb transcripts were up-regulated in chondrocytes (c) of the ceratohyal in fam20b^b1127 (H,K) and xylt1^b1128 (I,L) mutants, but were not detectable in wild types (G,J) at 72 hpf. Transcript levels for ptch2 were increased in the perichondrium of fam20b^b1127 (N) and xylt1^b1128 (O) mutants, compared to wild types (M) at 72 hpf, whereas no obvious differences in levels of ptch1 expression in perichondria were apparent (P–R). Abbreviations: c = chondrocytes; pc = perichondrium.

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Acknowledgments

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