ZFIN Image: Jing et al., 2009, Fig. S2

Image

Figure Caption

Fig. S2 ako functions partially non-cell-autonomously in photoreceptor morphogenesis and survival. (A-C′) Confocal images of transverse cryosections through the retinae of mosaic animals. To generate genetic mosaics, blastomere transplantation was performed using the Tg(pax6-DF4:mCFP^q01) transgenic ako line as the donor, and a non-transgenic line as the host. Sections were stained with an anti-GFP antibody to visualize donor-derived cells (red). Both wild-type (A,B,C) and mutant (A′,B′,C′) donor-derived cells contribute to the PRCL at 3.5 (A,A′), 4 (B,B′) and 6 dpf (C,C′), indicating a degree of non-cell-autonomy. The green signal in some panels is not relevant to this analysis and originates from a GFAP-GFP transgene. Scale bars: 15 μm.

Acknowledgments

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