ZFIN Image: Carl et al., 2007, Fig. 2

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Figure Caption

Fig. 2 The mbl Mutation Can Activate Epithalamic Nodal Pathway Genes Epistatic to Loss of Spw Activity (A) The graph illustrates the percentage of embryos with wild-type (WT) left, reversed (rev) right, bilateral (bil), or not visible (nv) Nodal pathway gene expression in the epithalamus of wild-type (mbl sib) mbl (mbl^tm213/tm213), spw morphant (MoSpw/mbl sib), and mbl;spw morphant (MoSpw/mbl) embryos. The knockdown of Spw function results in the absence of lft1 and pitx2 expression only in the presence of wild-type Axin1. (B–E) Frontal views of the epithalamus (dorsal to the top) of 24s stage wild-type (mbl sib) mbl, spw morphant (MoSpw/mbl sib), and mbl;spw morphant (MoSpw/mbl) embryos analyzed for lft1 expression.

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Acknowledgments

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