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Fig. 4 The 3-O-sulfotransferases (3-OST) family is spatially restricted at 24 hr postfertilization. A: 3-OST-1 is expressed throughout the head and in the anterior somites. B: 3-OST-2 is expressed basally in the brain and specifically in the otic vesicle. C: 3-OST-3X is expressed in the hindbrain, spinal cord, branchial arches, pectoral fin, and lateral line primordial. D: 3-OST-3Z is expressed in the brain, spinal cord, pectoral fin, lateral line primordial, proctodeum, and dorsal fin fold. E: 3-OST-4 is expressed specifically in spinal cord neurons. F: 3-OST-5 is expressed specifically in the olfactory region and in posterior spinal cord neurons. G: 3-OST-6 is expressed specifically in the hindbrain. H: 3-OST-7 is expressed basally throughout the embryo and specifically in the posterior somites. BA, branchial arches; DFF, dorsal fin fold; FB, forebrain; HB, hindbrain; LLP, lateral line primordial; MB, midbrain; OE, olfactory epithelium; OT, otic vesicle; PF, pectoral fin; S, somites; SC, spinal cord; SCN, spinal cord neurons.

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