Gene

tmod4

ID

ZDB-GENE-991019-9

Name

tropomodulin 4 (muscle)

Symbol

tmod4 Nomenclature History

Previous Names

Sk-Tmod (1)
sktmod (1)
fa12b03
skeletal tropomodulin (1)
wu:fa12b03

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have tropomyosin binding activity. Involved in skeletal myofibril assembly. Predicted to localize to striated muscle thin filament. Is expressed in head muscle and myotome. Orthologous to human TMOD4 (tropomodulin 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Berger et al., 2014

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmod4 Human Ortholog

No data available

Associated With tmod4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR004934	Tropomodulin
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily

Domain Details Per Protein

Protein	Length	Leucine-rich repeat domain superfamily	Tropomodulin
UniProtKB:Q9PUQ6 InterPro	343

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tmod4-201 (1) Ensembl	Ensembl		1,717 nt	Select Tool
mRNA	tmod4-202 (1) Ensembl	Ensembl		2,087 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-tmod4	polyclonal	tmod4	IgG	Rabbit	WB	Proteintech	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations