Gene

cntn2

ID

ZDB-GENE-990630-12

Name

contactin 2

Symbol

cntn2 Nomenclature History

Previous Names

si:dz37k09.2
tag1
transiently expressed axonal glycoprotein

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable cell-cell adhesion mediator activity. Acts upstream of or within nervous system development and positive regulation of axon extension. Predicted to be active in axon and plasma membrane. Is expressed in cardiovascular system; nervous system; and trigeminal placode. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 5. Orthologous to human CNTN2 (contactin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

30 figures from 19 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d826 (21 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 15 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cntn2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
familial adult myoclonic epilepsy 5	Alliance	Epilepsy, early-onset, 5, with or without developmental delay	615400

Associated With cntn2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily