Gene
pes
- ID
- ZDB-GENE-990415-206
- Name
- pescadillo
- Symbol
- pes Nomenclature History
- Previous Names
-
- etID309792.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Acts upstream of or within exocrine pancreas development; oligodendrocyte differentiation; and regulation of cell cycle. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Is expressed in several structures, including alar plate midbrain region; digestive system; liver primordium; musculature system; and nervous system. Used to study Shwachman-Diamond syndrome. Orthologous to human PES1 (pescadillo ribosomal biogenesis factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56654 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Shwachman-Diamond syndrome | peshi2Tg/hi2Tg | standard conditions | Provost et al., 2012 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BRCT domain | BRCT domain superfamily | Pescadillo |
|---|---|---|---|---|
|
UniProtKB:P79741
|
583 |
Interactions and Pathways
No data available
Plasmids
No data available