Gene
nr2f1a
- ID
- ZDB-GENE-980526-115
- Name
- nuclear receptor subfamily 2, group F, member 1a
- Symbol
- nr2f1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in circulatory system development and endothelial cell proliferation. Predicted to localize to nucleus. Is expressed in several structures, including basal plate midbrain region; cardiovascular system; mesoderm; nervous system; and pharyngeal arch. Orthologous to human NR2F1 (nuclear receptor subfamily 2 group F member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76864 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bosch-Boonstra-Schaaf optic atrophy syndrome | Alliance | Bosch-Boonstra-Schaaf optic atrophy syndrome | 615722 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050274 | Nuclear hormone receptor family NR2 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR2 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q06725
|
411 | ||||||
|
UniProtKB:A0A8M9Q2V3
|
235 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nr2f1a-201
(1)
|
Ensembl | 2,994 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-nr2f1a | polyclonal | Rabbit |
|
1 |
Plasmids
No data available