Gene
adamts16
- ID
- ZDB-GENE-130530-760
- Name
- ADAM metallopeptidase with thrombospondin type 1 motif, 16
- Symbol
- adamts16 Nomenclature History
- Previous Names
-
- zmp:0000000757 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase activity. Involved in basement membrane disassembly and closure of optic fissure. Used to study coloboma. Is expressed in several structures, including digestive system; eye; muscle; optic cup; and pleuroperitoneal region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Cao et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| coloboma | AB + MO2-adamts16 | standard conditions | Cao et al., 2018 |
| coloboma | AB + MO1-adamts16 | standard conditions | Cao et al., 2018 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
- No data available
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-adamts16 | polyclonal | IgG | Rabbit |
|
Abcam plc
|
2 |
Plasmids
No data available
- Comparative Orthology
- Alliance