Gene
adamts16
- ID
- ZDB-GENE-130530-760
- Name
- ADAM metallopeptidase with thrombospondin type 1 motif, 16
- Symbol
- adamts16 Nomenclature History
- Previous Names
-
- zmp:0000000757 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity and metalloendopeptidase activity. Acts upstream of or within basement membrane disassembly and closure of optic fissure. Predicted to be located in extracellular region. Is expressed in several structures, including digestive system; eye; muscle; optic cup; and pleuroperitoneal region. Used to study coloboma.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Cao et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| coloboma | AB + MO2-adamts16 | standard conditions | Cao et al., 2018 |
| coloboma | AB + MO1-adamts16 | standard conditions | Cao et al., 2018 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
- No data available
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-adamts16 | polyclonal | IgG | Rabbit |
|
Abcam plc
|
2 |
Plasmids
No data available
- Comparative Orthology
- Alliance