Gene

kif21a

ID
ZDB-GENE-110411-237
Name
kinesin family member 21A
Symbol
kif21a Nomenclature History
Previous Names
  • si:ch1073-222m2.1
  • si:ch211-114o15.1
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to localize to kinesin complex and microtubule. Human ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles. Orthologous to human KIF21A (kinesin family member 21A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Riedmann et al., 2023
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Riedmann et al., 2023
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kif21a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital fibrosis of the extraocular muscles 1 Alliance Fibrosis of extraocular muscles, congenital, 1 135700
congenital fibrosis of the extraocular muscles 1 Alliance Fibrosis of extraocular muscles, congenital, 3B 135700
Associated With kif21a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Conserved_site IPR019821 Kinesin motor domain, conserved site
Domain IPR001752 Kinesin motor domain
Family IPR027640 Kinesin-like protein
Homologous_superfamily IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Kinesin-like protein Kinesin motor domain Kinesin motor domain, conserved site Kinesin motor domain superfamily P-loop containing nucleoside triphosphate hydrolase Quinoprotein alcohol dehydrogenase-like superfamily WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3AWT6 1591
UniProtKB:A0A8M3APB0 1575
UniProtKB:A0A8M2BAB6 1597
UniProtKB:F8W409 1598
UniProtKB:A0A8M9PNH0 1597
UniProtKB:A0A8M2BAD0 1554
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kif21a-201 (1) Ensembl 8,220 nt
mRNA kif21a-202 (1) Ensembl 4,584 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-kif21a polyclonal IgG Rabbit
  • IHC
  • WB
Biorbyt LLC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations