Gene

esamb

ID

ZDB-GENE-090916-1

Name

endothelial cell adhesion molecule b

Symbol

esamb Nomenclature History

Previous Names

esaml
zESAMb (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within cell-cell adhesion. Predicted to be located in membrane. Predicted to be active in adherens junction and plasma membrane. Is expressed in dorsal aorta and posterior cardinal vein. Orthologous to human ESAM (endothelial cell adhesion molecule).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Sauteur et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With esamb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with intracranial hemorrhage, seizures, and spasticity	620371

Associated With esamb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR042757	Endothelial cell-selective adhesion molecule
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Endothelial cell-selective adhesion molecule	Immunoglobulin domain subtype	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype 2	Immunoglobulin V-set domain
UniProtKB:E7FDC8 InterPro	436
UniProtKB:A0A8M3AHG6 InterPro	451
UniProtKB:A0A8M9Q5H7 InterPro	451
UniProtKB:A0A8M9Q1S7 InterPro	436

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	esamb-201 (1) Ensembl	Ensembl		2,668 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations