Gene
lmod3
- ID
- ZDB-GENE-090313-353
- Name
- leiomodin 3 (fetal)
- Symbol
- lmod3 Nomenclature History
- Previous Names
-
- si:dkey-90a13.2
- si:dkey-90a13.7 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have tropomyosin binding activity. Involved in muscle contraction and skeletal muscle thin filament assembly. Predicted to localize to striated muscle thin filament. Human ortholog(s) of this gene implicated in nemaline myopathy 10. Orthologous to human LMOD3 (leiomodin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Berger et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nemaline myopathy 10 | Alliance | Nemaline myopathy 10 | 616165 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| nemaline myopathy | AB + MO1-lmod3 + MO2-lmod3 | standard conditions | Yuen et al., 2014 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Leucine-rich repeat domain superfamily | Tropomodulin |
|---|---|---|---|
|
UniProtKB:A0A2R8QDE5
|
670 | ||
|
UniProtKB:A0A8M9QA08
|
670 | ||
|
UniProtKB:E7F7X0
|
670 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-lmod3 | polyclonal | IgG | Rabbit |
|
Proteintech
|
2 |
Plasmids
No data available