Gene

trpm4a

ID
ZDB-GENE-090302-3
Name
transient receptor potential cation channel, subfamily M, member 4a
Symbol
trpm4a Nomenclature History
Previous Names
  • trpm4 (1)
  • sb:eu515
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits calcium activated cation channel activity. Predicted to be involved in several processes, including cardiac conduction; regulation of T cell cytokine production; and vasoconstriction. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and progressive familial heart block type IB. Is expressed in brain; digestive system; integument; keratinocyte; and posterior pronephric duct. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpm4a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
erythrokeratodermia variabilis et progressiva 6 Alliance Erythrokeratodermia variabilis et progressiva 6 618531
progressive familial heart block type IB Alliance Progressive familial heart block, type IB 604559
Associated With trpm4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Domain IPR041491 TRPM, SLOG domain
Family IPR050927 Transient receptor potential cation channel M
Domain Details Per Protein
Protein Length Ion transport domain Transient receptor potential cation channel M TRPM, SLOG domain
UniProtKB:S5TRY1 1260
UniProtKB:A0A8M2BBK8 766
UniProtKB:A0A8M9PCR1 1031
UniProtKB:A0A8M2BB87 930
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA trpm4a-201 (1) Ensembl 4,659 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations