Gene
prkd1
- ID
- ZDB-GENE-080131-1
- Name
- protein kinase D1
- Symbol
- prkd1 Nomenclature History
- Previous Names
-
- PKD1 (1)
- si:dkeyp-47g2.1
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; calcium-dependent protein kinase C activity; and metal ion binding activity. Involved in regulation of angiogenesis and regulation of lymphangiogenesis. Predicted to localize to cytoplasm. Orthologous to human PRKD1 (protein kinase D1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hollenbach et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Hollenbach et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Congenital heart defects and ectodermal dysplasia | 617364 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR020454 | Diacylglycerol/phorbol-ester binding |
| Family | IPR015727 | Protein kinase C mu-related |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | C1-like domain superfamily | Diacylglycerol/phorbol-ester binding | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase, ATP binding site | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase C mu-related | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PPI9
|
878 | ||||||||||
|
UniProtKB:X1WHC7
|
886 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-prkd1 | polyclonal | Rabbit |
|
Santa Cruz Biotechnology, Inc.
|
2 |
Plasmids
No data available