Gene

gip

ID

ZDB-GENE-070720-10

Name

gastric inhibitory polypeptide

Symbol

gip Nomenclature History

Previous Names

zgc:165349

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Exhibits glucagon receptor binding activity. Involved in response to starvation. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is expressed in endocrine pancreas; intestine; and pancreas. Orthologous to human GIP (gastric inhibitory polypeptide).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gip Human Ortholog

No data available

Associated With gip Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000532	Glucagon/GIP/secretin/VIP
Family	IPR039078	Gastric inhibitory polypeptide

Domain Details Per Protein

Protein	Length	Gastric inhibitory polypeptide	Glucagon/GIP/secretin/VIP
UniProtKB:A1DPK4 InterPro	112

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	gip-201 (1) Ensembl	Ensembl		551 nt	Select Tool
mRNA	gip-202 (1) Ensembl	Ensembl		1,536 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-gip	polyclonal	gip		Rabbit	IHC		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations