Gene

myo1ca

ID

ZDB-GENE-070705-190

Name

myosin Ic, paralog a

Symbol

myo1ca Nomenclature History

Previous Names

si:ch211-69i14.4 (1)

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; actin binding activity; and motor activity. Involved in glomerulus development. Predicted to localize to several cellular components, including myosin complex; ruffle; and stereocilium membrane. Is expressed in brain; gut; myotome; notochord; and pronephric glomerulus. Orthologous to human MYO1C (myosin IC).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Arif et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Arif et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myo1ca Human Ortholog

No data available

Associated With myo1ca Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000048	IQ motif, EF-hand binding site
Domain	IPR010926	Class I myosin tail homology domain
Domain	IPR036072	Class I myosin, motor domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily