Gene

pnpo

ID
ZDB-GENE-060602-2
Name
pyridoxamine 5'-phosphate oxidase
Symbol
pnpo Nomenclature History
Previous Names
  • im:7138360 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have pyridoxamine-phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Orthologous to human PNPO (pyridoxamine 5'-phosphate oxidase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pnpo Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pyridoxamine 5'-phosphate oxidase deficiency Alliance Pyridoxamine 5'-phosphate oxidase deficiency 610090
Associated With pnpo Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site
Domain IPR011576 Pyridoxamine 5'-phosphate oxidase, putative
Domain IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal
Family IPR000659 Pyridoxamine 5'-phosphate oxidase
Homologous_superfamily IPR012349 FMN-binding split barrel
Domain Details Per Protein
Protein Length FMN-binding split barrel Pyridoxamine 5'-phosphate oxidase Pyridoxamine 5'-phosphate oxidase, conserved site Pyridoxamine 5'-phosphate oxidase, putative Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal
UniProtKB:A0A8M1P3D4 277
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pnpo-201 (1) Ensembl 2,155 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-pnpo polyclonal Rabbit
  • WB
GeneTex
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations