Gene
piwil2
- ID
- ZDB-GENE-060526-345
- Name
- piwi-like RNA-mediated gene silencing 2
- Symbol
- piwil2 Nomenclature History
- Previous Names
-
- zili (1)
- sb:eu354
- si:dkey-88f5.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits piRNA binding activity. Involved in several processes, including germ-line stem cell population maintenance; negative regulation of SMAD protein complex assembly; and piRNA metabolic process. Localizes to P granule and nucleus. Is expressed in axis; blastoderm; blastodisc; pharyngeal arch 3-7; and reproductive system. Orthologous to human PIWIL2 (piwi like RNA-mediated gene silencing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu354 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003100 | PAZ domain |
Domain | IPR003165 | Piwi domain |
Domain | IPR014811 | Argonaute, linker 1 domain |
Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
Homologous_superfamily | IPR036085 | PAZ domain superfamily |
Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
Domain Details Per Protein
Protein | Length | Argonaute, linker 1 domain | PAZ domain | PAZ domain superfamily | Piwi domain | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A2CEI6
|
1046 | ||||||
UniProtKB:A0A8M9PKJ0
|
1046 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
piwil2-201
(1)
|
Ensembl | 7182 nt | |
mRNA |
piwil2-202
(1)
|
Havana | 3464 nt | |
mRNA |
piwil2-203
(1)
|
Havana | 736 nt | |
mRNA |
piwil2-204
(1)
|
Ensembl | 3626 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
AB2-piwil2 | polyclonal | Rabbit |
|
2 | |||
Ab1-piwil2 | polyclonal | Rabbit |
|
2 |
Plasmids
No data available