Gene
kank1a
- ID
- ZDB-GENE-060526-215
- Name
- KN motif and ankyrin repeat domains 1a
- Symbol
- kank1a Nomenclature History
- Previous Names
-
- ankrd15 (1)
- kank1
- si:dkey-146l2.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of actin filament polymerization. Predicted to localize to cytoplasm and cytoskeleton. Human ortholog(s) of this gene implicated in spastic quadriplegia. Is expressed in several structures, including fin; lateral plate mesoderm; notochord; optic vesicle; and otic placode. Orthologous to human KANK1 (KN motif and ankyrin repeat domains 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hensley et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spastic quadriplegic cerebral palsy 2 | Alliance | Cerebral palsy, spastic quadriplegic, 2 | 612900 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kank1a-202
(1)
|
Ensembl | 5,969 nt | ||
| mRNA |
kank1a-203
(1)
|
Ensembl | 712 nt | ||
| ncRNA |
kank1a-003
(1)
|
Ensembl | 613 nt |
Interactions and Pathways
No data available
Plasmids
No data available