Gene
slc17a8
- ID
- ZDB-GENE-060503-416
- Name
- solute carrier family 17 member 8
- Symbol
- slc17a8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in equilibrioception; regulation of synapse structure or activity; and vestibular reflex. Predicted to localize to excitatory synapse and integral component of synaptic vesicle membrane. Is expressed in hair cell; hair cell anterior macula; inner ear; neuromast; and neuromast hair cell. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Orthologous to human SLC17A8 (solute carrier family 17 member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 25 | Alliance | Deafness, autosomal dominant 25 | 605583 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Major facilitator superfamily | Major facilitator superfamily domain | Major Facilitator Superfamily Sodium/Anion Cotransporter | MFS transporter superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q1L8X9
|
590 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc17a8-201
(1)
|
Ensembl | 1,773 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-slc17a8 | polyclonal | Rabbit |
|
8 |
Plasmids
No data available