Gene

dmc1

ID
ZDB-GENE-060331-93
Name
DNA meiotic recombinase 1
Symbol
dmc1 Nomenclature History
Previous Names
  • zgc:136628
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have DNA binding activity; DNA-dependent ATPase activity; and recombinase activity. Predicted to be involved in DNA recombination; chromosome organization involved in meiotic cell cycle; and response to ionizing radiation. Predicted to localize to condensed nuclear chromosome. Is expressed in ovary. Orthologous to human DMC1 (DNA meiotic recombinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dmc1 Human Ortholog
No data available
Associated With dmc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR013632 DNA recombination and repair protein Rad51-like, C-terminal
Domain IPR020587 DNA recombination and repair protein RecA, monomer-monomer interface
Domain IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
Family IPR011940 Meiotic recombination protein Dmc1
Family IPR016467 DNA recombination and repair protein, RecA-like
Homologous_superfamily IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain DNA recombination and repair protein Rad51-like, C-terminal DNA recombination and repair protein, RecA-like DNA recombination and repair protein RecA-like, ATP-binding domain DNA recombination and repair protein RecA, monomer-monomer interface DNA repair Rad51/transcription factor NusA, alpha-helical Meiotic recombination protein Dmc1 P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q50LF4 342
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dmc1-201 (1) Ensembl 1,350 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-dmc1 polyclonal Guinea pig
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations