Gene

lgsn

ID
ZDB-GENE-060312-26
Name
lengsin, lens protein with glutamine synthetase domain
Symbol
lgsn Nomenclature History
Previous Names
  • lgs (1)
  • gluld1 (1)
  • lengsin (1)
  • zgc:136604
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have glutamate-ammonia ligase activity. Involved in cell differentiation and lens morphogenesis in camera-type eye. Localizes to actin filament. Is expressed in lens. Orthologous to human LGSN (lengsin, lens protein with glutamine synthetase domain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Harding et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lgsn Human Ortholog
No data available
Associated With lgsn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008146 Glutamine synthetase, catalytic domain
Domain IPR008147 Glutamine synthetase, N-terminal domain
Homologous_superfamily IPR014746 Glutamine synthetase/guanido kinase, catalytic domain
Homologous_superfamily IPR036651 Glutamine synthetase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Glutamine synthetase, catalytic domain Glutamine synthetase/guanido kinase, catalytic domain Glutamine synthetase, N-terminal domain Glutamine synthetase, N-terminal domain superfamily
UniProtKB:Q29RF4 668
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lgsn-201 (1) Ensembl 2,297 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-lgsn polyclonal Rabbit
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations