Gene
fbxo7
- ID
- ZDB-GENE-050913-68
- Name
- F-box protein 7
- Symbol
- fbxo7 Nomenclature History
- Previous Names
-
- si:ch211-286m4.2
- zgc:114096
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have protein kinase binding activity. Involved in musculoskeletal movement. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Is expressed in brain; heart; and liver. Orthologous to human FBXO7 (F-box protein 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:114096 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Zhao et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Parkinson's disease 15 | Alliance | Parkinson disease 15, autosomal recessive | 260300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | F-box domain | F-box-like domain superfamily | F-box only protein 7 | PI31 proteasome regulator, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PHA1
|
485 | ||||
|
UniProtKB:Q4V8X6
|
486 |
Interactions and Pathways
No data available
Plasmids
No data available