Gene

ezrb

ID
ZDB-GENE-050803-1
Name
ezrin b
Symbol
ezrb Nomenclature History
Previous Names
  • ezr
  • cb567 (1)
  • ezrin2 (1)
  • vil2 (1)
  • wu:fc05c03 (1)
  • wu:fj31d06 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have actin binding activity. Involved in several processes, including cell migration involved in gastrulation; epiboly; and regulation of cilium assembly. Predicted to localize to cytoskeleton. Is expressed in several structures, including anterior axial hypoblast; digestive system; hatching gland; nervous system; and prechordal plate. Orthologous to human EZR (ezrin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ezrb Human Ortholog
No data available
Associated With ezrb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019747 FERM conserved site
Domain IPR000299 FERM domain
Domain IPR011259 Ezrin/radixin/moesin, C-terminal
Domain IPR018979 FERM, N-terminal
Domain IPR018980 FERM, C-terminal PH-like domain
Domain IPR019748 FERM central domain
Domain IPR019749 Band 4.1 domain
Domain IPR041789 ERM family, FERM domain C-lobe
Domain IPR046810 Ezrin/radixin/moesin, alpha-helical domain
Family IPR000798 Ezrin/radixin/moesin-like
Family IPR011174 Ezrin/radixin/moesin
Homologous_superfamily IPR008954 Moesin tail domain superfamily
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR014352 FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR035963 FERM superfamily, second domain
Domain Details Per Protein
Protein Length Band 4.1 domain ERM family, FERM domain C-lobe Ezrin/radixin/moesin Ezrin/radixin/moesin, alpha-helical domain Ezrin/radixin/moesin, C-terminal Ezrin/radixin/moesin-like FERM/acyl-CoA-binding protein superfamily FERM central domain FERM conserved site FERM, C-terminal PH-like domain FERM domain FERM, N-terminal FERM superfamily, second domain Moesin tail domain superfamily PH-like domain superfamily Ubiquitin-like domain superfamily
UniProtKB:Q5TZG5 583
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ezrb-201 (1) Ensembl 6,561 nt
mRNA ezrb-202 (1) Ensembl 2,812 nt
mRNA ezrb-203 (1) Ensembl 608 nt
mRNA ezrb-204 (1) Ensembl 182 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ezrb polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations