Gene
pde6ga
- ID
- ZDB-GENE-050522-144
- Name
- phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a
- Symbol
- pde6ga Nomenclature History
- Previous Names
-
- zgc:112320 (1)
- zgc:153837
- zgc:158528
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have 3',5'-cyclic-nucleotide phosphodiesterase activity and cGMP binding activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Is expressed in epiphysis; retinal photoreceptor layer; and retinal rod cell. Orthologous to human PDE6G (phosphodiesterase 6G) and PDE6H (phosphodiesterase 6H).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112320 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Retinal cGMP phosphodiesterase, gamma subunit | Retinal cGMP phosphodiesterase, gamma subunit superfamily |
|---|---|---|---|
|
UniProtKB:Q502C6
|
86 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance