Gene
akr1a1b
- ID
- ZDB-GENE-050417-118
- Name
- aldo-keto reductase family 1, member A1b (aldehyde reductase)
- Symbol
- akr1a1b Nomenclature History
- Previous Names
-
- zgc:110225 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in cellular detoxification of aldehyde. Predicted to localize to apical plasma membrane and cytosol. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Li et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018170 | Aldo/keto reductase, conserved site |
Domain | IPR023210 | NADP-dependent oxidoreductase domain |
Family | IPR020471 | Aldo-keto reductase |
Family | IPR044481 | Aldo-keto reductase family 1 member A1 |
Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
Protein | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | Aldo-keto reductase family 1 member A1 | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:Q568L5
|
324 | |||||
UniProtKB:A0A8M2BDN5
|
351 | |||||
UniProtKB:A0A8M2BDV8
|
326 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
akr1a1b-201
(1)
|
Havana | 754 nt | |
mRNA |
akr1a1b-202
(1)
|
Havana | 1091 nt | |
mRNA |
akr1a1b-203
(1)
|
Havana | 910 nt | |
mRNA |
akr1a1b-204
(1)
|
Havana | 760 nt | |
mRNA |
akr1a1b-205
(1)
|
Havana | 1182 nt | |
mRNA |
akr1a1b-207
(1)
|
Havana | 803 nt | |
ncRNA |
akr1a1b-007
(1)
|
Havana | 877 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-akr1a1b | polyclonal | Guinea pig |
|
1 |
Plasmids
No data available