Gene
insl3
- ID
- ZDB-GENE-050310-5
- Name
- insulin-like 3 (Leydig cell)
- Symbol
- insl3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor binding activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in cryptorchidism. Is expressed in several structures, including endocrine system; female organism; gut; heart; and male organism. Orthologous to human INSL3 (insulin like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Crespo et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cryptorchidism | Alliance | Cryptorchidism | 219050 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Insulin, conserved site | Insulin family | Insulin-like | Insulin-like INSL3/INSL4 | Insulin-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q2P9V5
|
153 |
Interactions and Pathways
No data available
Plasmids
No data available