Gene
sirt7
- ID
- ZDB-GENE-050208-612
- Name
- sirtuin 7
- Symbol
- sirt7 Nomenclature History
- Previous Names
-
- si:ch211-258l4.6 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have NAD-dependent histone deacetylase activity (H3-K18 specific) and transcription corepressor activity. Involved in hematopoietic progenitor cell differentiation. Predicted to localize to nuclear telomeric heterochromatin. Is expressed in retina. Orthologous to human SIRT7 (sirtuin 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu987 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Huang et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DHS-like NAD/FAD-binding domain superfamily | NAD-dependent sirtuin protein deacylases | Sirtuin family | Sirtuin family, catalytic core domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QUG9
|
405 |
Interactions and Pathways
No data available
Plasmids
No data available