Gene

prnpb

ID
ZDB-GENE-041221-2
Name
prion protein b
Symbol
prnpb Nomenclature History
Previous Names
  • PrP-1 (1)
  • PrP1 (1)
  • prnprs1
  • stPrP-1 (1)
  • zgc:123004
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Involved in several processes, including calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; epiboly involved in gastrulation with mouth forming second; and homophilic cell adhesion via plasma membrane adhesion molecules. Localizes to cell surface and plasma membrane. Is expressed in cranial ganglion; eye; floor plate; and forebrain.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prnpb Human Ortholog
No data available
Associated With prnpb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR036924 Prion/Doppel beta-ribbon domain superfamily
Domain Details Per Protein
Protein Length Prion/Doppel beta-ribbon domain superfamily
UniProtKB:Q3BDW0 606
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prnpb-201 (1) Ensembl 2,399 nt
mRNA prnpb-202 (1) Ensembl 2,132 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prnp monoclonal IgG1 , k Mouse
Prionics AG
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations