Gene

bik

ID

ZDB-GENE-041210-181

Name

BCL2 interacting killer

Symbol

bik Nomenclature History

Previous Names

si:dkey-31f5.6

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Involved in positive regulation of apoptotic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in ataxia telangiectasia; breast cancer; colon cancer; and prostate cancer. Is expressed in eye; gut; kidney; ovary; and trunk. Orthologous to human BIK (BCL2 interacting killer).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bik Human Ortholog

No data available

Associated With bik Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR024579	Bcl-2-interacting killer

Domain Details Per Protein

Protein	Length	Bcl-2-interacting killer
UniProtKB:Q5RGV7 InterPro	153
UniProtKB:Q5RGV6 InterPro	154

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	bik-201 (1) Ensembl	Ensembl		811 nt	Select Tool
mRNA	bik-202 (1) Ensembl	Ensembl		528 nt	Select Tool
mRNA	bik-203 (1) Ensembl	Ensembl		736 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
ab1-bik	polyclonal	bik		Rabbit		AnaSpec	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations