Gene
pgrmc1
- ID
- ZDB-GENE-041114-91
- Name
- progesterone receptor membrane component 1
- Symbol
- pgrmc1 Nomenclature History
- Previous Names
-
- fa94d03
- wu:fa94d03
- wu:fq25e02
- zgc:103577
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Involved in regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to localize to endomembrane system and membrane. Is expressed in several structures, including digestive system; gonad; heart; integument; and muscle. Orthologous to human PGRMC1 (progesterone receptor membrane component 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103577 (1 image)
- IMAGE:3715953 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| cataract | s1020tEt; s1984tTg + MO1-pgrmc1 | standard conditions | Jones et al., 2021 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome b5-like heme/steroid binding domain | Cytochrome b5-like heme/steroid binding domain superfamily |
|---|---|---|---|
|
UniProtKB:Q5U3G0
|
179 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pgrmc1-201
(1)
|
Ensembl | 2,373 nt | ||
| mRNA |
pgrmc1-202
(1)
|
Ensembl | 555 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-pgrmc1 | polyclonal | Rabbit |
|
2 |
Plasmids
No data available