Gene
ptgs2b
- ID
- ZDB-GENE-041014-323
- Name
- prostaglandin-endoperoxide synthase 2b
- Symbol
- ptgs2b Nomenclature History
- Previous Names
-
- Cox-2b (1)
- si:dkey-97o5.6
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Enables peroxidase activity. Acts upstream of or within cellular response to organic cyclic compound. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including female organism; gonad; kidney; male organism; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; arthritis (multiple); cardiovascular system disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EGF-like domain | Haem peroxidase, animal-type | Haem peroxidase domain superfamily, animal type | Haem peroxidase superfamily | Oxylipin biosynthesis and metabolism |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5RI06
|
606 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptgs2b-201
(1)
|
Ensembl | 2,556 nt |
Interactions and Pathways
No data available
Plasmids
No data available