Gene

stk25a

ID

ZDB-GENE-041010-92

Name

serine/threonine kinase 25a

Symbol

stk25a Nomenclature History

Previous Names

stk25b (1)
zgc:92836

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within axis elongation and heart development. Predicted to be active in Golgi apparatus. Is expressed in cranial ganglion and pharyngeal arch. Orthologous to human STK25 (serine/threonine kinase 25).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92836 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Yoruk et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stk25a Human Ortholog

No data available

Associated With stk25a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR048288	Programmed cell death protein 10, dimerisation domain
Family	IPR050629	STE20/SPS1-related Proline-Alanine-rich Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR046409	Programmed cell death protein 10, dimerisation domain superfamily

Domain Details Per Protein

Protein	Length	Programmed cell death protein 10, dimerisation domain	Programmed cell death protein 10, dimerisation domain superfamily	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	STE20/SPS1-related Proline-Alanine-rich Kinase
UniProtKB:F8W562 InterPro	421
UniProtKB:A0A8M2BDG3 InterPro	424

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	stk25a-203 (1) Ensembl	Ensembl	1,922 nt	Select Tool ZFIN BLAST
ncRNA	stk25a-003 (1) Ensembl	Ensembl	886 nt	Select Tool ZFIN BLAST
ncRNA	stk25a-004 (1) Ensembl	Ensembl	665 nt	Select Tool ZFIN BLAST
ncRNA	stk25a-005 (1) Ensembl	Ensembl	509 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations