Gene

polr2a

ID
ZDB-GENE-041008-78
Name
RNA polymerase II subunit A
Symbol
polr2a Nomenclature History
Previous Names
  • im:7136071 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to localize to RNA polymerase II, core complex. Is expressed in blastomere. Orthologous to human POLR2A (RNA polymerase II subunit A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With polr2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities 618603
Associated With polr2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000722 RNA polymerase, alpha subunit
Domain IPR006592 RNA polymerase, N-terminal
Domain IPR007066 RNA polymerase Rpb1, domain 3
Domain IPR007073 RNA polymerase Rpb1, domain 7
Domain IPR007075 RNA polymerase Rpb1, domain 6
Domain IPR007080 RNA polymerase Rpb1, domain 1
Domain IPR007081 RNA polymerase Rpb1, domain 5
Domain IPR007083 RNA polymerase Rpb1, domain 4
Family IPR045867 DNA-directed RNA polymerase, subunit beta-prime
Homologous_superfamily IPR038120 RNA polymerase Rpb1, funnel domain superfamily
Homologous_superfamily IPR038593 RNA polymerase Rpb1, domain 7 superfamily
Homologous_superfamily IPR042102 RNA polymerase Rpb1, domain 3 superfamily
Homologous_superfamily IPR044893 RNA polymerase Rpb1, clamp domain superfamily
Repeat IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic
Domain Details Per Protein
Protein Length DNA-directed RNA polymerase, subunit beta-prime RNA polymerase, alpha subunit RNA polymerase II, heptapeptide repeat, eukaryotic RNA polymerase, N-terminal RNA polymerase Rpb1, clamp domain superfamily RNA polymerase Rpb1, domain 1 RNA polymerase Rpb1, domain 3 RNA polymerase Rpb1, domain 3 superfamily RNA polymerase Rpb1, domain 4 RNA polymerase Rpb1, domain 5 RNA polymerase Rpb1, domain 6 RNA polymerase Rpb1, domain 7 RNA polymerase Rpb1, domain 7 superfamily RNA polymerase Rpb1, funnel domain superfamily
UniProtKB:A0A0R4IMS9 1965
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA polr2a-201 (1) Ensembl 8,182 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-polr2a monoclonal IgG2a Mouse
  • IHC
Santa Cruz Biotechnology, Inc.
Covance
8
Ab2-polr2a monoclonal IgG1 Mouse
Santa Cruz Biotechnology, Inc.
Covance
4
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations