Gene
agrp
- ID
- ZDB-GENE-040817-1
- Name
- agouti related neuropeptide
- Symbol
- agrp Nomenclature History
- Previous Names
-
- agrp1 (1)
- si:dkey-193l8.2
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits melanocortin receptor binding activity and neuropeptide hormone activity. Involved in several processes, including developmental growth; neuropeptide signaling pathway; and positive regulation of feeding behavior. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is expressed in brain; female organism; hypophysis; hypothalamus; and periventricular nucleus. Orthologous to human AGRP (agouti related neuropeptide).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Agouti | Agouti domain | Agouti domain superfamily |
---|---|---|---|---|
UniProtKB:A0A8M1P467
|
127 |
Interactions and Pathways
No data available
Plasmids
No data available