Gene
mipa
- ID
- ZDB-GENE-040801-41
- Name
- major intrinsic protein of lens fiber a
- Symbol
- mipa Nomenclature History
- Previous Names
-
- mip1
- aqp0a (1)
- zgc:100858
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Enables water channel activity. Acts upstream of or within lens fiber cell morphogenesis and water transport. Predicted to be active in plasma membrane. Is expressed in eye; lens; lens fiber cell; and solid lens vesicle. Human ortholog(s) of this gene implicated in cataract and cataract 15 multiple types. Orthologous to human MIP (major intrinsic protein of lens fiber).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cataract 15 multiple types | Alliance | Cataract 15, multiple types | 615274 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aquaporin-like | Aquaporin transporter | Major intrinsic protein | Major intrinsic protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q6DEI6
|
263 |
Interactions and Pathways
No data available
Plasmids
No data available