Gene
tnnc1b
- ID
- ZDB-GENE-040625-62
- Name
- troponin C type 1b (slow)
- Symbol
- tnnc1b Nomenclature History
- Previous Names
-
- stnnc
- ssTnC (1)
- zgc:86932
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity; calcium ion binding activity; and calcium-dependent protein binding activity. Involved in cardiac muscle contraction. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Z; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 13. Is expressed in adaxial cell; heart; musculature system; solid lens vesicle; and somite. Orthologous to human TNNC1 (troponin C1, slow skeletal and cardiac type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6899234 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1Z | Alliance | Cardiomyopathy, dilated, 1Z | 611879 |
| hypertrophic cardiomyopathy 13 | Alliance | Cardiomyopathy, hypertrophic, 13 | 613243 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair |
|---|---|---|---|---|
|
UniProtKB:Q6IQ64
|
161 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnnc1b-201
(1)
|
Ensembl | 874 nt |
Interactions and Pathways
No data available
Plasmids
No data available