Gene
cdk2
- ID
- ZDB-GENE-040426-2741
- Name
- cyclin dependent kinase 2
- Symbol
- cdk2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; protein phosphorylation; and regulation of G2/M transition of mitotic cell cycle. Predicted to act upstream of or within phosphorylation. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in nervous system and pharyngeal arch 3-7 skeleton. Human ortholog(s) of this gene implicated in prostate cancer and renal cell carcinoma. Orthologous to human CDK2 (cyclin dependent kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56598 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Yang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin-dependent kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZWB1
|
298 |
Interactions and Pathways
No data available
Plasmids