Gene
sort1a
- ID
- ZDB-GENE-040426-2329
- Name
- sortilin 1a
- Symbol
- sort1a Nomenclature History
- Previous Names
-
- sort1
- zgc:85953 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to be involved in Golgi to endosome transport; endocytosis; and vesicle organization. Predicted to localize to Golgi apparatus and integral component of membrane. Is expressed in cardiovascular system; central nervous system; pigment cell; and tail bud. Orthologous to human SORT1 (sortilin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7158646 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Low density lipoprotein cholesterol level QTL6] | 613589 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sortilin, C-terminal | Sortilin, N-terminal | VPS10 | VPS10-related sortilin family receptors | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6NUT7
|
814 | |||||
|
UniProtKB:A0A0R4IEP6
|
815 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sort1a-202
(1)
|
Ensembl | 4,687 nt | ||
| mRNA |
sort1a-203
(1)
|
Ensembl | 5,938 nt | ||
| ncRNA |
sort1a-002
(1)
|
Ensembl | 734 nt |
Interactions and Pathways
No data available
Plasmids
No data available