Gene
marcksl1a
- ID
- ZDB-GENE-040426-2146
- Name
- MARCKS-like 1a
- Symbol
- marcksl1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity. Involved in cartilage development; central nervous system development; and neural retina development. Predicted to localize to cytoplasm; cytoskeleton; and plasma membrane. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; head mesenchyme; nervous system; and neural plate. Orthologous to human MARCKSL1 (MARCKS like 1).
- Genome Resources
- Note
-
Prieto and Zolessi (2017) suggest that the "a" and "b" designations, established in 2012, of the marcksl1 paralogs, should be reversed based on structural and functional similarities to the MARCKSL1 genes. No changes were made because the "a" and "b" designations are not reflective of priority in discovery, function or structure but are designated based on the evidence available at the time of the nomenclature event for the evolutionary and syntenic relationship to the ancestral gene.
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb575 (24 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Prieto et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR002101 | Myristoylated alanine-rich C-kinase substrate MARCKS |
Domain Details Per Protein
| Protein | Length | Myristoylated alanine-rich C-kinase substrate MARCKS |
|---|---|---|
|
UniProtKB:Q6PD99
|
213 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
marcksl1a-201
(1)
|
Ensembl | 1,694 nt |
Interactions and Pathways
No data available
Plasmids
No data available