Gene
pyroxd1
- ID
- ZDB-GENE-040426-1732
- Name
- pyridine nucleotide-disulphide oxidoreductase domain 1
- Symbol
- pyroxd1 Nomenclature History
- Previous Names
-
- ryroxd1 (1)
- zgc:73254
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to nucleus and sarcomere. Human ortholog(s) of this gene implicated in myofibrillar myopathy 8. Is expressed in female organism and trunk musculature. Orthologous to human PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73254 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from O'Grady et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| myofibrillar myopathy 8 | Alliance | Myopathy, myofibrillar, 8 | 617258 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023753 | FAD/NAD(P)-binding domain |
| Domain | IPR041575 | NADH-rubredoxin oxidoreductase, C-terminal |
| Family | IPR050260 | FAD-dependent oxidoreductase |
| Homologous_superfamily | IPR016156 | FAD/NAD-linked reductase, dimerisation domain superfamily |
| Homologous_superfamily | IPR036188 | FAD/NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | FAD-dependent oxidoreductase | FAD/NAD-linked reductase, dimerisation domain superfamily | FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain superfamily | NADH-rubredoxin oxidoreductase, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6PBT5
|
490 | |||||
|
UniProtKB:A0A0R4IEM7
|
485 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ryroxd1 |
|
Abmart
|
2 |
Plasmids
No data available